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Apostle MagTouch Technology

The Apostle MagTouch instrument is an automatic extraction and purification system for nucleic acids from various types of biological samples collected in multiple transport media. It can absorb, transfer and release magnetic beads by a magnetic rod and magnetic rod sleeve to separate magnetic beads and samples. The operation is automatic, fast and simple.

Apostle MiniGenomics and MagTouch Technologies in COVID-19 Testing

Apostle COVID-19 RNA Extraction System Applied in the Effective Detection of SARS-CoV-2

Ed. Horner S. Application Note.

The current coronavirus disease 2019 (COVID-19) pandemic started in late 2019. COVID-19 is the result of severe acute respiratory syndrome 2 (SARS-CoV-2) virus contraction. COVID-19 is often accompanied by a wide range of symptoms including fever, cough, and shortness of breath. The SARS-CoV-2 virus consists of a ~30 kb RNA genome encoding for 15 proteins, including the spike protein that enables the virus to enter host cells. The current gold standard qualitative detection method, qRT-PCR, reverse transcribes the viral RNA into cDNA, which is subsequently amplified and quantitated.

This application note illustrates the effective detection of SARS-CoV-2 using the Apostle COVID-19 Viral RNA Isolation Automation System and qRT-PCR in clinical lab settings. This system uses efficient MiniGenomics magnetic nanoparticle technology for fast extraction and purification of viral nucleic acids from various types of biological samples collected in transport media. The proficient and consistent systems provide reliable test results to individuals that contribute to COVID-19 pandemic relief.

To date, our clients have processed more than 10 million swabs in various CAP/CLIA clinical labs in the United States. 

“Apostle COVID-19 RNA Extraction System is a fast and reliable solution for SARS-CoV-2 viral RNA extraction. We look forward to continuing the collaboration with Apostle and providing high quality COVID-19 tests for our community.” commented by Harry Gao, MD, PhD, DABMG, FACMG, Lab Director and Chief Scientific Officer of Fulgent Genetics.

Included in: FDA EUA Summary: Fulgent COVID-19 by RT-PCR TEST(FULGENT THERAPEUTICS).  For In vitro Diagnostic Use. Rx Only. For use under Emergency Use Authorization (EUA) only. US FDA. April 12, 2021. 

Apostle MagTouch and MiniMax Technologies in cfDNA Applications

The Apostle MagTouch 2000 Nucleic Acids Extraction Automation System can be utilized with the Apostle MiniMax High Efficiency Cell-Free DNA Isolation Kit to automate the cfDNA isolation process, and significantly improve the lab flow and efficiency.

The system has been utilized by our clients to extract cell-free DNA and/or RNAs from various volumes of plasma samples.  The system is also easily programmable to adapt with various laboratory settings and needs.  Some example protocols are listed below.