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As used in the following high-profile studies:

Served over 20 million people from all over the country since 2017

Serving Public Health and Life Sciences

Apostle develops and provides best-in-class nucleic acid isolation and preservation technologies.

Apostle technologies have been applied in many world-class R&D studies, clinical laboratory settings, and public health response and surveillance. To date, over 20 million samples have been successfully processed using our technologies, and the number is quickly growing.
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Best-in-class performance: cfDNA isolation
Best-in-class performance: cfDNA isolation

MagTouch

The MagTouch 2000 instrument is an automatic extraction and purification system for nucleic acids from various types of biological samples collected in multiple transport media. It can absorb, transfer and release magnetic beads by a magnetic rod and magnetic rod sleeve to separate magnetic beads and samples. The operation is automatic, fast and simple. Compared with our earlier model 1000, the new model 2000 is easier to use, more robust, and has a smaller foot print.

Best-in-class performance: cfDNA isolation

Apostle MiniMax High Efficiency Cell-Free DNA Isolation Kit

The ability to isolate and analyze circulating cell free DNA (cfDNA) at very low concentrations is becoming increasingly important, particularly in non-invasive prenatal test (NIPT), early cancer detection, and infectious disease diagnosis. Highly efficient isolation of cfDNA from complexed biological medium is a crucial step for subsequent cfDNA analysis. Apostle MiniMax technology offers a best-in-class efficiency and purity compared with conventional technologies to capture and isolate the circulating cell-free genetic materials. Its superb performance has been extensively validated. Please review the examples of publications and performance data.
  • As applied in: Efficient detection and post-surgical monitoring of colon cancer with a multi-marker DNA methylation liquid biopsy. Jin et al. PNAS Feb 2, 2021;118(5) e2017421118.
  • Performance independently confirmed as: "(Figure 4) Most notably, the Apostle particles outperformed all others, achieving almost 2-fold higher recovery yields than the particles supplied in the X kit".SLAS Technology Available online 17 Dec 2021
  • More publications
Apostle MiniMax High Efficiency Cell-Free DNA Isolation Kit (Standard Edition) (5mL x 50 preps)Powered by Apostle MiniMax technology, Apostl..
$476.86
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Apostle MiniMax Cell-Free DNA Blood Collection Tube

Powered by Apostle MiniMax technology, Apostle MiniMax cfDNA Blood Collection Tube (BCT) is an excellent tool for blood cfDNA preservation during blood collection, storage and transport.
This is achieved through Apostle MiniMax cfDNA BCT’s ability to:
  • Prevent the release and contamination of genomic DNA from cells in blood during storage and transportation.
  • Preserve existing cfDNA in blood from degradation.
  • Prevent existing cfDNA in blood from cross-linking with with other biomolecules (i.e. protein).
In summary, high cfDNA quality can be preserved with Apostle MiniMax cfDNA Blood Collection Tube for downstream applications, through the prevention of cfDNA degradation, crosslingking and contamination.
Superior performance: cfRNA isolation

Apostle MiniMax High Efficiency Cell-Free RNA Isolation Kit

  • Apostle MiniMax High Efficiency cfRNA Isolation Kit offers superior isolation efficiency of cell-free RNAs between 17 nt to 1000 nt, without phenol or chloroform.
  • Ready for a broad range of subsequent applications, including sequencing, PCR, etc.
  • It is suitable for processing samples collected in various major blood collection tubes, especially which will prevent RNA degradation during storage.
Next-generation Enrichment of Short DNA fragments for NIPT and Oncology Research

Apostle MiniEnrich Short Fragments Enrichment Kit

Precise DNA sizing can boost sequencing efficiency, reduce cost, improve data quality, and even allow sequencing of low-input samples, while current pervasive DNA sizing approaches are incapable of differentiating DNA fragments under 200 bp with high resolution (<20 bp). The Apostle MiniEnrich Short Fragments Enrichment Kit is a simple, automatable, high-resolution DNA size enrichment workflow on a magnetic nano-platform to exploit this 20 bp size difference and to enrich fetal DNA fragments from maternal blood.

  • As published in: High-resolution DNA size enrichment using a magnetic nano-platform and application in non-invasive prenatal testing. Zhang et al. Analyst July 2020, 145, 5733-5739 (PDF)
Next-generation purification, size selection, and long-read size selection

Apostle MiniEnrich Carboxyl Beads for Purification

Next-generation purification, size selection, and long-read size selection.

The Apostle MiniEnrich Purification Beads is designed for purification and clean-up of DNA fragments from the contaminants in NGS and molecular biology workflows. It can be used on samples after DNA isolation, fragmentation, PCR amplification, cloning, library preparation, etc. With proprietary Apostle MiniEnrich technology, the kit is featured for its more efficient removal of contaminants and recovery of DNA fragments of interest than current market-leading products.

  • As published in: High-resolution DNA size enrichment using a magnetic nano-platform and application in non-invasive prenatal testing. Zhang et al. Analyst July 2020, 145, 5733-5739 (PDF)
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Apostle MagTouch 96 Deep-Well Plate

We have built a strong global supply chain, and provide an ample and stable supply of all the reagents and consumables required for our automatic system.
Our plastic consumables come at a high quality and a guaranteed 30-50% less cost compared with other brands on market.
  • High quality: Equal or better results compared with other brands.
  • Lower cost: Guaranteed 30% - 50% less cost than other brands.
  • Fully compatible: Standard formats fully compatible with broad brands' nucleic acids isolation automation platforms.
  • Fully validated: trusted by tests in over 10 million samples.

About Us

Apostle Inc is a biotechnology company in Pleasanton, CA and San Jose, CA, a provider of innovative technologies and services for public health and life sciences. Apostle develops and provides best-in-class nucleic acid isolation and preservation technologies, including innovative technologies in the space of liquid biopsy - the sampling and analysis of non-solid biological tissue, primarily blood, often utilizing circulating free DNA (cfDNA) as a biomarker.
Headquarters: 3589 Nevada St, Pleasanton, CA 94566
San Jose Site: 160 E Tasman Dr, STE 116, San Jose, CA 95134

News & Tweets

April 10, 2023

[Nature Communications] Integrative modeling of tumor genomes and epigenomes for enhanced cancer diagnosis by cell-free DNA

Nature Communications just published a clinical study, including 2125 cancer patients, 9 cancer types, using the Apostle Minimax cfDNA technology. This study demonstrates the ability of its model to detect early-stage cancers using cfDNA, including those of pancreatic origin, with high sensitivity that is comparable to that of late-stage detection.  Congratulations to this clinical research team. To date, the Apostle Minimax cfDNA technology has been used in 2 articles published in Nature Medicine, 1 in Nature Communications, 1 in Science Translational Medicine, 1 in PNAS, and over 50 scientific articles in different journals.   ....read more
Nature Communications just published a clinical study, including 2125 cancer patients, 9 cancer types, using the Apostle Minimax cfDNA technology. This study demonstrates the ability of its model to detect early-stage cancers using cfDNA, including those of pancreatic origin, with high sensitivity that is comparable to that of late-stage detection. Congratulations to this clinical research team. To date, the Apostle Minimax cfDNA technology has been used in 2 articles published in Nature Medicine, 1 in Nature Communications, 1 in Science Translational Medicine, 1 in PNAS, and over 50 scientific articles in different journals.